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A Couple of Ycombinator's Startups

Last year I mentioned reports that the startup incubator Ycombinator was thinking of getting into the biopharma field. Here's a look at the current crop of potential companies. One thing that stands...

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Rotten Rottlerin

Here's one of the problems with the various schemes to do "deep learning" using the published scientific literature: a fair proportion of that literature is junk. This is not news, of course, and to...

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Review of Reviews

Several papers of interest, in the "catching up with the literature" vein. For you stapled peptide fans, here's a review of their possible therapeutic uses, with what's been accomplished so far. And...

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CRISPR Gene Editing in Human Embryos: Not So Fast

As you'll have heard, the rumors that CRISPR/Cas9 experiments had been performed on human embryonic tissue have turned out to be true. The recent calls for a temporary moratorium on such work were said...

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Human CRISPR

Biocentury has a roundup of reactions to the recent human CRISPR paper: There's no dispute that because the technology is in its infancy, much more work needs to be done to establish its safety....

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A Young Blood Controversy

The recent revival of interest in the way that the blood from younger animals (and people?) can improve the health of older ones came bundled with a particular protein candidate for the effect, GDF11....

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Crappy Antibodies: Available Now, and for the Foreseeable Future

I made a brief mention of this article yesterday, but I wanted to highlight it. It's a look, from Nature New, at the broader implications of the antibody problem in research. Antibodies are, of course,...

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Guess What: Your Peers Are Already Reviewing You

Looks like there are biologists who are getting a chance to figure out what social media can do to communication in their field. Nature News reports on the response to a PNAS paper published late last...

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Inside Moderna (A Little Bit)

Here's a look at Moderna, the mRNA-based company who have been signed so many gigantic deals over the last few years. From the outside, I've always regarded them as enigmatic, and I'm apparently not...

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Artificial Intelligence For Biology?

A new paper in PLoS Computational Biology is getting a lot of attention (which event, while not trying to be snarky about it, is not something that happens every day). Here's the press release, which I...

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Chemical Probe Compounds: Time to Get Real

There's a new paper on chemical probes out in Nature Chemical Biology, and right off, I have to disclose a conflict of interest. I'm a co-author, and I'm glad to be one. (Here's a comment at Nature...

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